Proteomics? Proteins, yes...
...but we want them all , we want them all at once!
Our lab employs modern proteomic analyses to study global changes of human proteome in order to describe molecular mechanisms of human diseases, to look for disease biomarkers or to identify novel drug targets. We analyze complex biological samples such as tissue samples, body fludis or cell cultures. Using various hi-res separation methods such as peptide IEF-IPG or 1-D or 2-D liquid chromatography combined with top-notch mass spectrometry (MS) we can monitor quantitative and qualitative changes of thousands of proteins in a single sample.
Our current projects:
- Membrane proteome of pediatric brain tumors
- Key upragulated proteins of rare neuroendocrine tumors as future therapeutic targets.
Key players and markers of advanced heart failure
- Identification of diagnostic markers for aortic dissection.